Tropocells® PRP
Platelet-Rich Plasma (PRP) is an innovative and promising approach in tissue regeneration. PRP is defined as an autologous concentrated preparation of plateletsin a small volume of plasma. PRP owes its therapeutic interest to the crucial instrumental role of growth factors released by platelets granules which possess multiple regenerative properties. The autologous nature of Tropocells® PRP guarantees its excellent safety profile.
PRP is thought to promote physiological healing and rapid soft and hard tissue regeneration by delivering high concentrations of growth factors essential for connective tissue healing; regenerating and repairing bone, tendon, cartilage and ligament; promoting development of new blood vessels and stimulating wound healing.
PRP is effective in cases of:
- Orthopedic injuries (including sports injuries)
- Meniscus\labrum injuries
- Pain resulting from a herniated disc
- torn ligament\tendon\muscle
- Pain after orthopedic surgeries
- Joint inflammations such as: tennis\golf elbow, bursitis, tendinitis
- Chronic pain from diseases such as: hyper flexibility, hEDS, osteoarthritis (OA)
- Hard-to-heal wound\diabetic wound
Advantages of PRP Therapy in Orthopedics & Sports Medicine
- PRP initiates connective tissue healing, bone and joint surface regeneration and repair, promotes development of new blood vessels and stimulates wound healing.
- PRP provides significant improvement in symptoms
- Safety – PRP is a very safe procedure; it is non-allergenic and without risk of transmissible diseases
- PRP accelerates healing and may delay or eliminate the need for surgery
- May be combined with other treatments to stimulate biological healing effects
Unique Biological Profile
The specially-designed Tropocells® Separator Gel produces an optimum PRP profile:
- Low Granulocytes: Virtually eliminating granulocytes from PRP, which are not considered beneficial in terms of regeneration process and may contribute to a catabolic effect by secreting catabolic mediators, including metalloproteinases
- Low RBCs: erythrocytes have been shown to significantly decrease fibroblast proliferation and augment apoptosis in vitro
- Monocyte Enrichment helps in attenuating inflammation and the beginning of the regeneration process
- Increasing collagen expression and enhance anabolic effects of PRP
- High Platelet Yield: A proprietary anticoagulant and specialized tube coating help maximize platelet yield so only a lower volume of blood is needed
PRP Preparation Using Tropocells® PRP
1
Collect blood directly into Tropocells PRP vacuum tube containing separation gel and anticoagulant
2
Centrifuge for 10 min at 1500 g.
3
Gel separates platelets from PPP, RBC and granulocytes. Platelets reside on top of the gel. Insert the vented needle into the tube
4
Remove a portion of PPP to achieve higher platelet concentration (optional)
5
Resuspend platelets in the remaining plasma to generate PRP by inverting the liquid a few times against the tube wall
6
Draw PRP for use
Gel separates platelets from PPP, RBC and granulocytes. Platelets reside on top of the gel. Insert the vented needle into the tube
Centrifuge for 10 min at 1500 g.
Collect blood directly into Tropocells PRP vacuum tube containing separation gel and anticoagulant
Remove a portion of PPP to achieve higher platelet concentration (optional)
Resuspend platelets in the remaining plasma to generate PRP by inverting the liquid a few times against the tube wall
Draw PRP for use
Features and Benefits of The Tropocells® PRP System
Effectiveness :
- The Tropocells® system enables high platelet yield
- Rapid and simple preparation process with a single 10-minutes spin time
- Customizable Platelet Concentration for specific clinical applications
- Specially designed accessories for operation room setting
Safety and Quality :
- Closed, biocompatible and xeno-free system minimizing safety concerns
- Approved medical device by the European (CE) and USA (FDA) Regulatory Authorities (FDA clearance for orthopedic applications only)
- Manufactured in clean rooms, under EN ISO 13485:2016 Quality System International Standards